InVivoMab anti-mouse CTLA-4 (CD152) BE0032-R100mg from Bio X Cell

Other available quantities: Available in 1, 5, 10, 25, 50, 100 mg and bulk sizes. Academic discount available.

Endotoxin: <2EU/mg (<0.002EU/µg), Determined by LAL gel clotting assay

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(1) Reversal of indoleamine 2,3-dioxygenase-mediated cancer immune suppression by systemic kynurenine depletion with a therapeutic enzymeNature biotechnologySeptember 1, 2018Triplett TA, Garrison KC, Marshall N, Donkor M, Blazeck J, Lamb C, Qerqez A, Dekker JD, Tanno Y, Lu WC, et al.

(2) The viral context instructs the redundancy of costimulatory pathways in driving CD8(+) T cell expansioneLifeAugust 11, 2015Welten SP, Redeker A, Franken KL, Oduro JD, Ossendorp F, Čičin-Šain L, Melief CJ, Aichele P, Arens R.

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(4) Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4European journal of immunologyFebruary 1, 2015Pletinckx K, Vaeth M, Schneider T, Beyersdorf N, Hünig T, Berberich-Siebelt F, Lutz MB.

(5) CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer modelsCancer researchSeptember 15, 2014Zhu Y, Knolhoff BL, Meyer MA, Nywening TM, West BL, Luo J, Wang-Gillam A, Goedegebuure SP, Linehan DC, DeNardo DG.

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(7) Differential kinetics of antigen dependency of CD4+ and CD8+ T cellsJournal of immunology (Baltimore, Md. : 1950)April 15, 2014Rabenstein H, Behrendt AC, Ellwart JW, Naumann R, Horsch M, Beckers J, Obst R.

(9) Targeting CD73 enhances the antitumor activity of anti-PD-1 and anti-CTLA-4 mAbsClinical cancer research : an official journal of the American Association for Cancer ResearchOctober 15, 2013Allard B, Pommey S, Smyth MJ, Stagg J.

(11) CD4+ natural regulatory T cells prevent experimental cerebral malaria via CTLA-4 when expanded in vivoPLoS pathogensDecember 9, 2010Haque A, Best SE, Amante FH, Mustafah S, Desbarrieres L, de Labastida F, Sparwasser T, Hill GR, Engwerda CR.

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InVivoMab anti-mouse CTLA-4 (CD152)